FROZEN EMBRYO TRANSFER (FET)

A frozen embryo transfer, commonly known as FET, is the process of transferring frozen embryos obtained from previous IVF cycle. This procedure is gaining popularity due to its safety and pregnancy success rates.

Indications

  • If couple have extra embryos from previous IVF cycle.
  • If couple want another Child.
  • Couple goes for embryo’s genetic screening (PGT/PGS).
  • Patient is at high risk of OHSS (Ovarian Hyperstimulation Syndrome)
  • Fresh embryo transfer cancelled.
  • If couple opt for an embryo donor.

Process

  • Couple undergoes the standard Ovarian Stimulation for 12-15 days.
  • Oocytes are retrieved from the ovaries of patient or from the donor.
  • Fertilization is done in the laboratory and embryos are cultured for few days (generally from day 3 till day 5).
  • Embryos are then frozen or cryopreserved (freezed) either at day 3 or day 5.
  • Before a cryopreserved embryo can be transferred the lining of the uterus (called the endometrium) has to be monitored to be able to support the embryo.
  • Once the endometrium is prepared, embryos are warmed in the laboratory by the embryologist and checks if the embryo has survived the warming process (referred as thawing).
  • Thawed or warmed embryos are then transferred to the uterus.

Frozen Embryo Transfer Success Rates

For patients 35 or younger, there is a 60% pregnancy rate per embryo transfer, whereas women over the age of 40 have a 20% pregnancy rate per embryo transfer.

Risks

  • Fertility drug side effects
  • Ovarian hyperstimulation syndrome and other egg retrieval risks
  • Spotting, cramps or discomfort from embryo transfer
  • Multiple pregnancy if more than one embryo is implanted

Frequently asked questions

Q1. What are the benefits of FET?

ANS:- Benefits of FET include reducing pregnancy risks of fresh embryo transfer IVF cycles, permitting the uterus environment to return to normal after egg retrieval, and allowing for genetic screening(if required).

Q2. Is FET a painful process?

ANS:- No. It is virtually a painless process with little bit of cramping possible.

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